National Toxicology Program

Items received in response to the request for public comment in the October 2, 2008 Federal Register Notice (Federal Register Notice 73 FR 57358):

• Bisphenol AF
• Dimethylamine borane
• Ethylene glycol 2-ethylhexyl ether
• Hydroxyurea
• L-beta-Methylaminoalanine
• Triclosan

The NTP invites interested parties to submit written comments or supplementary information on the nominated substances and preliminary study recommendations that appear in the table below. The NTP welcomes toxicology study information from completed, ongoing, or anticipated studies, as well as information on current U.S. production levels, use or consumption patterns, human exposure, environmental occurrence, or public health concerns for any of the nominated substances. The NTP is interested in identifying appropriate animal and non-animal experimental models for mechanistic-based research, including genetically modified rodents and high-throughput in vitro test methods, and as such, solicits comments regarding the use of specific in vivo and in vitro experimental approaches to address questions relevant to the nominated substances and issues under consideration. Comments should be submitted by May 23, 2008; however, the NTP welcomes comments or additional information on these study nominations at any time.

The NTP will not respond to submitted comments; however, all information received will be become part of the official record that the NTP considers in its ongoing review of these nominations. Persons submitting comments should include their name, affiliation, mailing address, phone, fax, e-mail address, and sponsoring organization (if any) with the submission. Written submissions will be made available on the NTP website here as they are received.

Correspondence should be addressed to:
Dr. Scott A. Masten
Director, Office of Nomination and Selection
National Toxicology Program
National Institute of Environmental Health Sciences

P.O. Box 12233, MD K2-02
Research Triangle Park, NC 27709
(919) 541-5710 (voice)
(919) 541-3647 (fax)

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