Descriptions of NTP Study Types

Studies in Genetically Modified Models

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GMM-1 pdf
Toxicology Studies of Aspartame (CAS No. 22839-47-0) in Genetically Modified (FVB Tg.AC Hemizygous) and B6.129-Cdkn2atm1Rdp (N2) deficient Mice and Carcinogenicity Studies of Aspartame in Genetically Modified [B6.129-Trp53tm1Brd (N5) Haploinsufficient] Mice (Feed Studies) (Report Date: October 2005) 
GMM-2 pdf
Toxicology Studies of Acesulfame Potassium (CAS No. 55589-62-3) in FVB/N-TgN(v-Ha-ras)Led (Tg.AC) Hemizygous Mice and Carcinogenicity Studies of Acesulfame Potassium in B6.129-Trp53tm1Brd (N5) Haploinsufficient Mice (Feed Studies)  (Report Date: October 2005) 
GMM-3 pdf Toxicology Studies of Trimethylolpropane Triacrylate (Technical Grade) (CAS No. 15625-89-5) in F344/N Rats, B6C3F1 Mice, and Genetically Modified (FVB Tg.AC Hemizygous) Mice (Dermal Studies)  (Report Date: October 2005) 
GMM-4 pdf Toxicology Studies of Pentaerythritol Triacrylate (Technical Grade) (CAS No. 3524-68-3) in F344/N Rats, B6C3F1 Mice, and Genetically Modified (FVB Tg.AC Hemizygous) Mice (Dermal Studies)  (Report Date: October 2005) 
GMM-5 pdf
Toxicology Studies of Bromodichloromethane (CAS No. 75-27-4) in Genetically Modified (FVB Tg.AC Hemizygous) Mice (Dermal, Drinking Water, and Gavage Studies) and Carcinogenicity Studies of Bromodichloromethane in Genetically Modified [B6.129-Trp53tm1Brd (N5) Haploinsufficient] Mice (Drinking Water and Gavage Studies)  (Report Date: May 2007) 
GMM-06 pdf
Toxicology Study of Sodium Bromate (CAS No. 7789-38-0) in Genetically Modified (FVB Tg.AC Hemizygous) Mice (Dermal and Drinking Water Studies) and Carcinogenicity Studies of Sodium Bromate in Genetically Modified [B6.129-Trp53tm1Brd (N5) Haploinsufficient] Mice (Drinking Water Studies)  (Report Date: May 2007) 
GMM-07
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Toxicology Studies of Allyl Bromide (CAS No. 106-95-6) in Genetically Modified (FVB Tg.AC Hemizygous) Mice and Carcinogenicity Studies of Allyl Bromide in Genetically Modified [B6.129-Trp53tm1Brd (N5) Haploinsufficient] Mice (Dermal and Gavage Studies  (Report Date: April 2008) 
GMM-08
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Toxicology and Carcinogenesis Study of Benzene (CAS No. 71-43-2) in Genetically Modified Haploinsufficient p16Ink4a/p19Arf Mice (Gavage Study) (Report Date: October 2007)
GMM-09
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Toxicology Studies of Dicyclohexylcarbodiimide (CAS No. 538-75-0) in F344/N Rats, B6C3F1 Mice, and Genetically Modified (FVB Tg.AC HEMIZYGOUS) Mice and Carcinogenicity Study of Dicyclohexylcarbodiimide in Genetically Modified [B6.129-Trp53tm1Brd (N5) Haploinsufficient] Mice (Dermal Studies)
(Report Date: September 2007)
GMM-10 pdf
Toxicology Study of Diispropylcarbodiimide (CAS No. 693-13-0) in Genetically Modified (FVB Tg.AC Hemizygous) Mice and Carcinogenicity Study of Diispropylcarbodiimide in Genetically Modified [B6.129-Trp53tm1Brd (N5) Haploinsufficient Mice (Dermal Studies) (Report Date: March 2007)
GMM-11 pdf
Toxicology Studies of Dichloroacetic Acid (CAS No. 79-43-6) in Genetically Modified (FVB Tg.AC Hemizygous) Mice (Dermal and Drinking Water Studies) and Carcinogenicity Studies of Dichloroacetic Acid in Genetically Modified [B6.129-Trp53tm1Brd (N5) Haploinsufficient Mice (Drinking Water Studies) (Report Date: April 2007)
GMM-12
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Toxicology and Carcinogenesis Study of Phenolphthalein (CAS No. 77-09-8) in Genetically Modified Haploinsufficient p16Ink4a/p19Arf Mice (Report Date: December 2007)
GMM-13
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Genetically Modified Model Report of the Toxicology and Carcinogenesis Study of Glycidol (CAS No. 556-52-5) in Genetically Modified Haploinsufficient p16Ink4a/p19Arf Mice (Gavage Study) (Report Date: November 2007)
GMM-14

Toxicology and Carcinogenesis of 3´-Azido-3´-Deoxythymidine (AZT) (CAS No. 30516-87-1) Genetically Modified C3B6.129F1-Trp53tm1Brd N12 Haploinsufficient Mice (in utero and postnatal gavage studies) - DRAFTAdobe Portable Document Format(2.8 Mb)

GMM-15
pdf Toxicology Study of Senna (CAS No. 8013-11-4) in IN C57BL/6NTAC MICE and Toxicology and Carcinogenesis of Senna Genetically Modified C3B6.129F1-Trp53tm1Brd N12 Haploinsufficient Mice (Feed Studies) - (Report Date: April 2012)

GMM-16

Toxicology and Carcinogenesis Studies of Mixtures of 3′-Azido-3′-Deoxythymidine (AZT), Lamivudine (3TC), and Nevirapine (NVP) (CAS Nos. 30516-87-1, 134678-17-4, 129618-40-2)in Genetically Modified C3B6.129F1-Trp53tm1Brd N12 Haploinsufficient Mice (in Utero and Postnatal Gavage Studies) - DRAFTAdobe Portable Document Format(5.5 Mb)

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